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- Alpha Kappa Psi
- Alpha Pi Mu
- Arnold Air Society: O'Neil Squadron
- Asian Student Union
- Army ROTC
- Alpha Sigma Kappa: Women in Technical Studies
- Apparel, Merchandising, and Design Graduate Student Association
- Ames Flyers
- American Cancer Society On Campus
- Archery Club
- American Nuclear Society Student Section
- Alternative Breaks
- Al Éxito Collegiate
- Astrophotography Club
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- Ivy Student Council
- IEEE-Eta Kappa Nu
- Indian Students' Association
- Institute of Electrical and Electronics Engineers
- Institute of Industrial & Systems Engineers (IISE)
- Interfraternity Council
- Interior Design Student Association (IDSA)
- International Student Council
- Iowa Stat-ers
- Iranian Students' and Scholars' Association
- Investment Group
- International Student Ambassadors Club
- Industrial Technology Club
- IMPACT (Innovators Making Positive Advances in Creative Technologies)
- Iowa Bandmasters Association
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- Supply Chain Management Club
- Student Government
- Sigma Chi
- Ski and Snowboard Club
- Society of Hispanic Professional Engineers
- Student-Athlete Advisory Committee (SAAC)
- Solar Car
- Sigma Lambda Beta International Fraternity Inc.
- Student American Veterinary Medical Association Chapter
- Student Veterans of America
- Students Helping Rescue Animals
- Softball Club (Women)
- Students Helping Our Peers (SHOP)
- Swim Club
- Sports Business Club
- Sports Media Club